IARC Monographs evaluation of the carcinogenicity of some aromatic amines and related compounds

The results of the recent IARC Monographs evaluation of the carcinogenicity of some aromatic amines and related compounds have now been published in The Lancet Oncology. This summary article presents the conclusions of IARC Monographs Meeting 127. Because of the coronavirus disease (COVID-19) pandemic, the meeting was held remotely.

The Working Group evaluated ortho-anisidine (and ortho-anisidine hydrochloride), ortho-nitroanisole, aniline (and aniline hydrochloride), and cupferron.

Aniline, ortho-nitroanisole, and ortho-anisidine were previously evaluated by the Working Group in 1987, 1996, and 1999, respectively. The remaining agents were evaluated by the Working Group for the first time.

The full scientific assessment will be published as Volume 127 of the IARC Monographs.

IARC Monographs Volume 127 Working Group
Carcinogenicity of some aromatic amines and related compounds
Lancet Oncol, Published online 25 June 2020;
https://doi.org/10.1016/S1470-2045(20)30375-2

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