HOME
Donate now
EN FR
EN FR

Epigenomics and Mechanisms Branch (EGM)

Publications

All recent publications: 2025-2021

View Key Publications

  1. Mulisa G, Pero-Gascon R, McCormack V, Bisanz JE, Talukdar FR, Abebe T, et al. (2025). Multiple mycotoxin exposure assessment through human biomonitoring in an esophageal cancer case-control study in the Arsi-Bale districts of Oromia region of Ethiopia. Int J Hyg Environ Health. 263: 114466. https://doi.org/10.1016/j.ijheh.2024.114466 PMID: 39306897
  2. Al-Soneidar WA, Harper S, Coutlee F, Gheit T, Tommasino M, Nicolau B (2024). Prevalence of Alpha, Beta, and Gamma Human Papillomaviruses in Patients With Head and Neck Cancer and Noncancer Controls and Relation to Behavioral Factors. J Infect Dis. 229(4): 1088-1096. https://doi.org/10.1093/infdis/jiad335 PMID: 37584283
  3. Berrington de Gonzalez A, Masten SA, Bhatti P, Fortner RT, Peters S, Santonen T, et al. (2024). Advisory Group recommendations on priorities for the IARC Monographs. Lancet Oncol. 25(5): 546-548. https://doi.org/10.1016/S1470-2045(24)00208-0 PMID: 38621402
  4. Boni SP, Tenet V, Horo A, Heideman DAM, Bleeker MCG, Tanon A, et al. (2024). High-risk human papillomavirus distribution according to human immunodeficiency virus status among women with cervical cancer in Abidjan, Cote d’Ivoire, 2018 to 2020. Int J Cancer. 154(6): 962-968. https://doi.org/10.1002/ijc.34774 PMID: 37942579
  5. Ceylan A, Uyar R, Çelik D, Rafieerad A, Çinar OO, Summak GY, et al. (2024). Spatial transcriptomics reveals the interplay between cancer and immune cells directed by MXene quantum dots. Nano Today. 56: 13. https://doi.org/ARTN 102285 10.1016/j.nantod.2024.102285
  6. Chavanel B, Virard F, Cahais V, Renard C, Sirand C, Smits KM, et al. (2024). Genome-scale mutational signature analysis in archived fixed tissues. Mutat Res Rev Mutat Res. 794: 108512. https://doi.org/10.1016/j.mrrev.2024.108512 PMID: 39216514
  7. Choudhary P, Monasso GS, Karhunen V, Ronkainen J, Mancano G, Howe CG, et al. (2024). Maternal educational attainment in pregnancy and epigenome-wide DNA methylation changes in the offspring from birth until adolescence. Mol Psychiatry. 29(2): 348-358. https://doi.org/10.1038/s41380-023-02331-5 PMID: 38052982
  8. Chung F, Zavadil J (2024). New risk factors and molecular landscapes of hepatic angiosarcoma in the Taiwanese population(dagger). J Pathol. 262(1): 1-3. https://doi.org/10.1002/path.6224 PMID: 37929656
  9. Chung FF, Khoueiry R, Salle A, Cuenin C, Boskovic M, Herceg Z (2024). Sodium arsenite-induced DNA methylation alterations exacerbated by p53 knockout in MCF7 cells. Heliyon. 10(21): e39548. https://doi.org/10.1016/j.heliyon.2024.e39548 PMID: 39512451
  10. Cortez Cardoso Penha R, Sexton Oates A, Senkin S, Park HA, Atkins J, Holcatova I, et al. (2024). Understanding the biological processes of kidney carcinogenesis: an integrative multi-omics approach. Mol Syst Biol. 20(12): 1282-1302. https://doi.org/10.1038/s44320-024-00072-3 PMID: 39592856
  11. Das S, Thakur S, Cahais V, Virard F, Claeys L, Renard C, et al. (2024). Molecular and cell phenotype programs in oral epithelial cells directed by co-exposure to arsenic and smokeless tobacco. bioRxiv. https://doi.org/10.1101/2024.10.14.618077 PMID: 39463997
  12. Dube Mandishora RS, Galati L, Reich RR, Combes JD, McKay-Chopin S, Makunike-Mutasa R, et al. (2024). Epstein-Barr Virus DNA Is Associated With Conjunctival Squamous Cell Carcinomas: A Case-Control Study From Zimbabwe. Open Forum Infect Dis. 11(4): ofae165. https://doi.org/10.1093/ofid/ofae165 PMID: 38623569
  13. Feng X, Goodley P, Alcala K, Guida F, Kaaks R, Vermeulen R, et al. (2024). Evaluation of risk prediction models to select lung cancer screening participants in Europe: a prospective cohort consortium analysis. Lancet Digit Health. 6(9): e614-e624. https://doi.org/10.1016/S2589-7500(24)00123-7 PMID: 39179310
  14. Galati L, Di Bonito P, Marinaro M, Chiantore MV, Gheit T (2024). HPV16 Phylogenetic Variants in Anogenital and Head and Neck Cancers: State of the Art and Perspectives. Viruses. 16(6): 15. https://doi.org/10.3390/v16060904 PMID: 38932197
  15. Gentile D, Chiummiento L, Santarsiere A, Funicello M, Lupattelli P, Rescifina A, et al. (2024). Targeting Viral and Cellular Cysteine Proteases for Treatment of New Variants of SARS-CoV-2. Viruses. 16(3): 16. https://doi.org/10.3390/v16030338 PMID: 38543704
  16. Ghantous A, Nussle SG, Nassar FJ, Spitz N, Novoloaca A, Krali O, et al. (2024). Epigenome-wide analysis across the development span of pediatric acute lymphoblastic leukemia: backtracking to birth. Mol Cancer. 23(1): 238. https://doi.org/10.1186/s12943-024-02118-4 PMID: 39443995
  17. Huybrechts I, Jacobs I, Biessy C, Aglago EK, Jenab M, Claeys L, et al. (2024). Associations between dietary mycotoxins exposures and risk of hepatocellular carcinoma in a European cohort. PLoS One. 19(12): e0315561. https://doi.org/10.1371/journal.pone.0315561 PMID: 39680546
  18. Karimi A, Mohebbi E, McKay-Chopin S, Hadji M, Rashidian H, Marzban M, et al. (2024). Association of opium use and tobacco smoking with alpha-, beta-, and gamma-human papillomavirus oral infection. Int J Cancer. 155(9): 1544-1548. https://doi.org/10.1002/ijc.35086 PMID: 39049799
  19. Kresovich JK, Guranich C, Houghton S, Qian J, Jones ME, Boutot ME, et al. (2024). Plasma prolactin and postmenopausal breast cancer risk: a pooled analysis of four prospective cohort studies. Breast Cancer Res. 26(1): 169. https://doi.org/10.1186/s13058-024-01922-6 PMID: 39593118
  20. Landberg R, Karra P, Hoobler R, Loftfield E, Huybrechts I, Rattner JI, et al. (2024). Dietary biomarkers-an update on their validity and applicability in epidemiological studies. Nutr Rev. 82(9): 1260-1280. https://doi.org/10.1093/nutrit/nuad119 PMID: 37791499
  21. Laskar RS, Qu C, Huyghe JR, Harrison T, Hayes RB, Cao Y, et al. (2024). Genome-wide association studies and Mendelian randomization analyses provide insights into the causes of early-onset colorectal cancer. Ann Oncol. 35(6): 523-536. https://doi.org/10.1016/j.annonc.2024.02.008 PMID: 38408508
  22. Li S, Spitz N, Ghantous A, Abrishamcar S, Reimann B, Marques I, et al. (2024). A Pregnancy and Childhood Epigenetics Consortium (PACE) meta-analysis highlights potential relationships between birth order and neonatal blood DNA methylation. Commun Biol. 7(1): 66. https://doi.org/10.1038/s42003-023-05698-x PMID: 38195839
  23. Maroui MA, Odongo GA, Mundo L, Manara F, Mure F, Fusil F, et al. (2024). Aflatoxin B1 and Epstein-Barr virus-induced CCL22 expression stimulates B cell infection. Proc Natl Acad Sci U S A. 121(16): e2314426121. https://doi.org/10.1073/pnas.2314426121 PMID: 38574017
  24. Mathian E, Drouet Y, Sexton-Oates A, Papotti MG, Pelosi G, Vignaud JM, et al. (2024). Assessment of the current and emerging criteria for the histopathological classification of lung neuroendocrine tumours in the lungNENomics project. ESMO Open. 9(6): 103591. https://doi.org/10.1016/j.esmoop.2024.103591 PMID: 38878324
  25. Mulisa G, Abebe T, Gutema B, Mahmuda J, Khan MAA, Gheit T, et al. (2024). Exploring Oesophageal Cancer in Ethiopia: Elevated Incidence in Females and Younger Cases. Cancer Rep (Hoboken). 7(12): e70048. https://doi.org/10.1002/cnr2.70048 PMID: 39665274
  26. Osorio JC, Andrade-Madrigal C, Gheit T, Corvalan AH, Aguayo F (2024). SLC7A11 Expression Is Up-Regulated in HPV- and Tobacco-Associated Lung Cancer. Int J Mol Sci. 25(24). https://doi.org/10.3390/ijms252413248 PMID: 39769017
  27. Ramadan F, Saab R, Ghamloush F, Khoueiry R, Herceg Z, Gomez L, et al. (2024). Exosome-Mediated Paracrine Signaling Unveils miR-1246 as a Driver of Aggressiveness in Fusion-Negative Rhabdomyosarcoma. Cancers (Basel). 16(9): 1652. https://doi.org/10.3390/cancers16091652 PMID: 38730605
  28. Ramasamy D, Thippannah M, Maharajan HRP, Balaiah M, Seshadri RA, Kodous AS, et al. (2024). Transcriptome-wide profiling identifies colon cancer-associated m6A transcripts and potential RNA methyl modifiers. Mol Biol Rep. 51(1): 299. https://doi.org/10.1007/s11033-024-09217-x PMID: 38345740
  29. Trischitta P, Tamburello MP, Venuti A, Pennisi R (2024). Pseudovirus-Based Systems for Screening Natural Antiviral Agents: A Comprehensive Review. Int J Mol Sci. 25(10): 5188. https://doi.org/10.3390/ijms25105188 PMID: 38791226
  30. Vijayraghavan S, Blouin T, McCollum J, Porcher L, Virard F, Zavadil J, et al. (2024). Widespread mutagenesis and chromosomal instability shape somatic genomes in systemic sclerosis. Nat Commun. 15(1): 8889. https://doi.org/10.1038/s41467-024-53332-z PMID: 39406724
  31. Alfano R, Zugna D, Barros H, Bustamante M, Chatzi L, Ghantous A, et al. (2023). Cord blood epigenome-wide meta-analysis in six European-based child cohorts identifies signatures linked to rapid weight growth. BMC Med. 21(1): 17. https://doi.org/10.1186/s12916-022-02685-7 PMID: 36627699
  32. Alsadi N, Yasavoli-Sharahi H, Mueller R, Cuenin C, Chung F, Herceg Z, et al. (2023). Protective Mechanisms of Polyphenol-Enriched Blueberry Preparation in Preventing Inflammation in the Skin against UVB-Induced Damage in an Animal Model. Antioxidants (Basel). 13(1): 19. https://doi.org/10.3390/antiox13010025 PMID: 38275645
  33. Awada Z, Cahais V, Cuenin C, Akika R, Silva Almeida Vicente AL, Makki M, et al. (2023). Waterpipe and cigarette epigenome analysis reveals markers implicated in addiction and smoking type inference. Environ Int. 182: 108260. https://doi.org/10.1016/j.envint.2023.108260 PMID: 38006773
  34. Awuchi CG, Nwozo OS, Aja PM, Odongo GA (2023). High-pressure acidified steaming with varied citric acid dosing can successfully detoxify mycotoxins. Food Sci Nutr. 11(6): 2677-2685. https://doi.org/10.1002/fsn3.3324 PMID: 37324899
  35. Chatterjee N, Sultana F, Roy R, Dey S, Naskar S, Dam A, et al. (2023). Prevalence of novel gamma HPV types 223 and 225 in oral cavity and skin of Indian normal and neoplastic participants. J Med Virol. 95(8): e29019. https://doi.org/10.1002/jmv.29019 PMID: 37543989
  36. Chung FF, Maldonado SG, Nemc A, Bouaoun L, Cahais V, Cuenin C, et al. (2023). Buffy coat signatures of breast cancer risk in a prospective cohort study. Clin Epigenetics. 15(1): 102. https://doi.org/10.1186/s13148-023-01509-6 PMID: 37309009
  37. Criscuolo E, Pala F, Siracusano G, Venuti A (2023). Editorial: Viral escape of mucosal immunity in sexually transmitted diseases. Front Immunol. 14: 1273515. https://doi.org/10.3389/fimmu.2023.1273515 PMID: 37680623
  38. Feng X, Muller DC, Zahed H, Alcala K, Guida F, Smith-Byrne K, et al. (2023). Evaluation of pre-diagnostic blood protein measurements for predicting survival after lung cancer diagnosis. EBioMedicine. 92: 104623. https://doi.org/10.1016/j.ebiom.2023.104623 PMID: 37236058
  39. Gheit T, Muwonge R, Lucas E, Galati L, Anantharaman D, McKay-Chopin S, et al. (2023). Impact of HPV vaccination on HPV-related oral infections. Oral Oncol. 136: 106244. https://doi.org/10.1016/j.oraloncology.2022.106244 PMID: 36402055
  40. Gihbid A, El Amrani A, Mouh FZ, Gheit T, Benhessou M, Amrani M, et al. (2023). Prevalence of Polyomaviruses and Herpesviruses in Moroccan Breast Cancer. Pathogens. 12(5): 640. https://doi.org/10.3390/pathogens12050640 PMID: 37242310
  41. Giuliani E, Rollo F, Cota C, Gheit T, Galati L, McKay-Chopin S, et al. (2023). Alpha, Beta, and Gamma Human Papillomaviruses in Genital Lichen Sclerosus: A Retrospective Cross-Sectional Study. J Low Genit Tract Dis. 27(3): 236-241. https://doi.org/10.1097/LGT.0000000000000741 PMID: 37052458
  42. Gregorio C, Thakur S, Camara Rivero R, Marcia Dos Santos Machado S, Cuenin C, Carreira C, et al. (2023). Telomere length assessment and molecular characterization of TERT gene promoter in periampullary carcinomas. Gene. 873: 147460. https://doi.org/10.1016/j.gene.2023.147460 PMID: 37150235
  43. Kadalayil L, Alam MZ, White CH, Ghantous A, Walton E, Gruzieva O, et al. (2023). Analysis of DNA methylation at birth and in childhood reveals changes associated with season of birth and latitude. Clin Epigenetics. 15(1): 148. https://doi.org/10.1186/s13148-023-01542-5 PMID: 37697338
  44. Karimi A, Jafari-Koshki T, Zehtabi M, Kargar F, Gheit T (2023). Predictive impact of human papillomavirus circulating tumor DNA in treatment response monitoring of HPV-associated cancers; a meta-analysis on recurrent event endpoints. Cancer Med. 12(17): 17592-17602. https://doi.org/10.1002/cam4.6377 PMID: 37492996
  45. Kutz JM, Rausche P, Rasamoelina T, Ratefiarisoa S, Razafindrakoto R, Klein P, et al. (2023). Female genital schistosomiasis, human papilloma virus infection, and cervical cancer in rural Madagascar: a cross sectional study. Infect Dis Poverty. 12(1): 89. https://doi.org/10.1186/s40249-023-01139-3 PMID: 37749705
  46. Lozar T, Keske A, Mandishora RSD, Yu QQ, Bailey A, Xu J, et al. (2023). Betapapillomaviruses in p16-Negative Vulvar Intraepithelial Lesions Associated with Squamous Cell Carcinoma. Viruses-Basel. 15(9): 1950. https://doi.org/10.3390/v15091950 PMID: 37766356
  47. Malagon T, Ribeiro AL, Montosa Nunes E, Gheit T, El-Zein M, Villa LL, et al. (2023). Betapapillomavirus natural history and co-detection with alphapapillomavirus in cervical samples of adult women. J Med Virol. 95(12): e29288. https://doi.org/10.1002/jmv.29288 PMID: 38054528
  48. Mangiante L, Alcala N, Sexton-Oates A, Di Genova A, Gonzalez-Perez A, Khandekar A, et al. (2023). Multiomic analysis of malignant pleural mesothelioma identifies molecular axes and specialized tumor profiles driving intertumor heterogeneity. Nat Genet. 55(4): 607-618. https://doi.org/10.1038/s41588-023-01321-1 PMID: 36928603
  49. Massafra R, Fanizzi A, Amoroso N, Bove S, Comes MC, Pomarico D, et al. (2023). Analyzing breast cancer invasive disease event classification through explainable artificial intelligence. Front Med (Lausanne). 10: 1116354. https://doi.org/10.3389/fmed.2023.1116354 PMID: 36817766
  50. Mundo L, Leoncini L, Accardi-Gheit R (2023). Epstein-Barr Virus Infection in Cancer. Cancers (Basel). 15(18): 7. https://doi.org/10.3390/cancers15184659 PMID: 37760627
  51. Robertson SE, Yasukawa M, Marchion DC, Xiong Y, Naqvi SMH, Gheit T, et al. (2023). Prevalence of viral DNA in high-grade serous epithelial ovarian cancer and correlation with clinical outcomes. PLoS One. 18(12): e0294448. https://doi.org/10.1371/journal.pone.0294448 PMID: 38039311
  52. Shahbazi R, Yasavoli-Sharahi H, Alsadi N, Sharifzad F, Fang S, Cuenin C, et al. (2023). Lentinula edodes Cultured Extract and Rouxiella badensis subsp. acadiensis (Canan SV-53) Intake Alleviates Immune Deregulation and Inflammation by Modulating Signaling Pathways and Epigenetic Mechanisms. Int J Mol Sci. 24(19): 23. https://doi.org/10.3390/ijms241914610 PMID: 37834058
  53. Shahbazi R, Yasavoli-Sharahi H, Mallet JF, Sharifzad F, Alsadi N, Cuenin C, et al. (2023). Novel Probiotic Bacterium Rouxiella badensis subsp. acadiensis (Canan SV-53) Modulates Gut Immunity through Epigenetic Mechanisms. Microorganisms. 11(10): 19. https://doi.org/10.3390/microorganisms11102456 PMID: 37894114
  54. Viguier M, Perals C, Poirier B, Battistella M, Aubin F, Bachelez H, et al. (2023). Human papilloma virus-16-specific CD8+ T-cell expansions characterize different clinical forms of lichen planus and not lichen sclerosus et atrophicus. Exp Dermatol. 32(6): 859-868. https://doi.org/10.1111/exd.14788 PMID: 36922453
  55. Bertinazzi M, Gheit T, Polesel J, McKay-Chopin S, Cutrone C, Sari M, et al. (2022). Clinical implications of alpha, beta, and gamma HPV infection in juvenile onset recurrent respiratory papillomatosis. Eur Arch Otorhinolaryngol. 279(1): 285-292. https://doi.org/10.1007/s00405-021-07040-9 PMID: 34453571
  56. Boskovic M, Roje B, Chung FF, Gelemanovic A, Cahais V, Cuenin C, et al. (2022). DNA Methylome Changes of Muscle- and Neuronal-Related Processes Precede Bladder Cancer Invasiveness. Cancers (Basel). 14(3): 17. https://doi.org/10.3390/cancers14030487 PMID: 35158756
  57. Cheikh IA, El-Baba C, Youssef A, Saliba NA, Ghantous A, Darwiche N (2022). Lessons learned from the discovery and development of the sesquiterpene lactones in cancer therapy and prevention. Expert Opin Drug Discov. 17(12): 1377-1405. https://doi.org/10.1080/17460441.2023.2147920 PMID: 36373806
  58. Claeys L, De Saeger S, Scelo G, Biessy C, Casagrande C, Nicolas G, et al. (2022). Mycotoxin Exposure and Renal Cell Carcinoma Risk: An Association Study in the EPIC European Cohort. Nutrients. 14(17): 3581. https://doi.org/10.3390/nu14173581 PMID: 36079840
  59. Das S, Thakur S, Korenjak M, Sidorenko VS, Chung FF, Zavadil J (2022). Aristolochic acid-associated cancers: a public health risk in need of global action. Nat Rev Cancer. 22(10): 576-591. https://doi.org/10.1038/s41568-022-00494-x PMID: 35854147
  60. de Andrade KC, Lee EE, Tookmanian EM, Kesserwan CA, Manfredi JJ, Hatton JN, et al. (2022). The TP53 Database: transition from the International Agency for Research on Cancer to the US National Cancer Institute. Cell Death Differ. 29(5): 1071-1073. https://doi.org/10.1038/s41418-022-00976-3 PMID: 35352025
  61. Dona MG, Gheit T, Chiantore MV, Vescio MF, Luzi F, Rollo F, et al. (2022). Prevalence of 13 polyomaviruses in actinic keratosis and matched healthy skin samples of immunocompetent individuals. Infect Agent Cancer. 17(1): 59. https://doi.org/10.1186/s13027-022-00472-w PMID: 36457033
  62. Dugue PA, Bodelon C, Chung FF, Brewer HR, Ambatipudi S, Sampson JN, et al. (2022). Methylation-based markers of aging and lifestyle-related factors and risk of breast cancer: a pooled analysis of four prospective studies. Breast Cancer Res. 24(1): 59. https://doi.org/10.1186/s13058-022-01554-8 PMID: 36068634
  63. El Abiead Y, Milford M, Schoeny H, Rusz M, Salek RM, Koellensperger G (2022). Power of mzRAPP-Based Performance Assessments in MS1-Based Nontargeted Feature Detection. Anal Chem. 94(24): 8588-8595. https://doi.org/10.1021/acs.analchem.1c05270 PMID: 35671103
  64. Froment P, Plotton I, Giulivi C, Fabre S, Khoueiry R, Mourad NI, et al. (2022). At the crossroads of fertility and metabolism: the importance of AMPK-dependent signaling in female infertility associated with hyperandrogenism. Hum Reprod. 37(6): 1207-1228. https://doi.org/10.1093/humrep/deac067 PMID: 35459945
  65. Galati L, Chiocca S, Duca D, Tagliabue M, Simoens C, Gheit T, et al. (2022). HPV and head and neck cancers: Towards early diagnosis and prevention. Tumour Virus Res. 14: 200245. https://doi.org/10.1016/j.tvr.2022.200245 PMID: 35973657
  66. Galati L, Combes JD, Le Calvez-Kelm F, McKay-Chopin S, Forey N, Ratel M, et al. (2022). Detection of Circulating HPV16 DNA as a Biomarker for Cervical Cancer by a Bead-Based HPV Genotyping Assay. Microbiol Spectr. 10(2): e0148021. https://doi.org/10.1128/spectrum.01480-21 PMID: 35225653
  67. Gholap D, Mhatre S, Chaturvedi P, Nair S, Gheit T, Tommasino M, et al. (2022). Prevalence of human papillomavirus types in head and neck cancer sub-sites in the Indian population. Ecancermedicalscience. 16: 1358. https://doi.org/10.3332/ecancer.2022.1358 PMID: 35510141
  68. Karanovic S, Ardin M, Tang Z, Tomic K, Villar S, Renard C, et al. (2022). Molecular profiles and urinary biomarkers of upper tract urothelial carcinomas associated with aristolochic acid exposure. Int J Cancer. 150(2): 374-386. https://doi.org/10.1002/ijc.33827 PMID: 34569060
  69. Karimi A, Mohebbi E, McKay-Chopin S, Rashidian H, Hadji M, Peyghambari V, et al. (2022). Human Papillomavirus and Risk of Head and Neck Squamous Cell Carcinoma in Iran. Microbiol Spectr. 10(4): e0011722. https://doi.org/10.1128/spectrum.00117-22 PMID: 35708339
  70. Manara F, Jay A, Odongo GA, Mure F, Maroui MA, Diederichs A, et al. (2022). Epigenetic Alteration of the Cancer-Related Gene TGFBI in B Cells Infected with Epstein-Barr Virus and Exposed to Aflatoxin B1: Potential Role in Burkitt Lymphoma Development. Cancers (Basel). 14(5). https://doi.org/10.3390/cancers14051284 PMID: 35267594
  71. Mena M, Wang X, Tous S, Quiros B, Clavero O, Alejo M, et al. (2022). Concordance of p16(INK4a) and E6*I mRNA among HPV-DNA-Positive Oropharyngeal, Laryngeal, and Oral Cavity Carcinomas from the ICO International Study. Cancers (Basel). 14(15): 12. https://doi.org/10.3390/cancers14153787 PMID: 35954451
  72. Reimann B, Martens DS, Wang C, Ghantous A, Herceg Z, Plusquin M, et al. (2022). Interrelationships and determinants of aging biomarkers in cord blood. J Transl Med. 20(1): 353. https://doi.org/10.1186/s12967-022-03541-1 PMID: 35945616
  73. Silver MJ, Saffari A, Kessler NJ, Chandak GR, Fall CHD, Issarapu P, et al. (2022). Environmentally sensitive hotspots in the methylome of the early human embryo. Elife. 11. https://doi.org/10.7554/eLife.72031 PMID: 35188105
  74. Simoens C, Gheit T, Ridder R, Gorbaslieva I, Holzinger D, Lucas E, et al. (2022). Accuracy of high-risk HPV DNA PCR, p16((INK4a)) immunohistochemistry or the combination of both to diagnose HPV-driven oropharyngeal cancer. BMC Infect Dis. 22(1): 676. https://doi.org/10.1186/s12879-022-07654-2 PMID: 35933382
  75. Solomon O, Huen K, Yousefi P, Kupers LK, Gonzalez JR, Suderman M, et al. (2022). Meta-analysis of epigenome-wide association studies in newborns and children show widespread sex differences in blood DNA methylation. Mutat Res Rev Mutat Res. 789: 108415. https://doi.org/10.1016/j.mrrev.2022.108415 PMID: 35690418
  76. Straub Hogan MM, Spieker AJ, Orejudos M, Gheit T, Herfs M, Tommasino M, et al. (2022). Pathological characterization and clinical outcome of penile intraepithelial neoplasia variants: a North American series. Mod Pathol. 35(8): 1101-1109. https://doi.org/10.1038/s41379-022-01020-y PMID: 35190664
  77. Talukdar FR, Abramovic I, Cuenin C, Carreira C, Gangane N, Sincic N, et al. (2022). A protocol for good quality genomic DNA isolation from formalin-fixed paraffin-embedded tissues without using commercial kits. Mol Biol Rep. 49(5): 4115-4121. https://doi.org/10.1007/s11033-022-07394-1 PMID: 35359238
  78. Talukdar FR, Escobar Marcillo DI, Laskar RS, Novoloaca A, Cuenin C, Sbraccia P, et al. (2022). Bariatric surgery-induced weight loss and associated genome-wide DNA-methylation alterations in obese individuals. Clin Epigenetics. 14(1): 176. https://doi.org/10.1186/s13148-022-01401-9 PMID: 36528638
  79. Thakur S, Cahais V, Turkova T, Zikmund T, Renard C, Stopka T, et al. (2022). Chromatin Remodeler Smarca5 Is Required for Cancer-Related Processes of Primary Cell Fitness and Immortalization. Cells. 11(5): 808. https://doi.org/10.3390/cells11050808 PMID: 35269430
  80. Venuti A, Romero-Medina MC, Melita G, Ceraolo MG, Brancaccio RN, Sirand C, et al. (2022). Lyon IARC Polyomavirus Displays Transforming Activities in Primary Human Cells. J Virol. 96(14): e0206121. https://doi.org/10.1128/jvi.02061-21 PMID: 35770990
  81. Vicente A, Novoloaca A, Cahais V, Awada Z, Cuenin C, Spitz N, et al. (2022). Cutaneous and acral melanoma cross-OMICs reveals prognostic cancer drivers associated with pathobiology and ultraviolet exposure. Nat Commun. 13(1): 4115. https://doi.org/10.1038/s41467-022-31488-w PMID: 35840550
  82. Vidican P, Perol O, Fevotte J, Fort E, Treilleux I, Belladame E, et al. (2022). Frequency of Asbestos Exposure and Histological Subtype of Ovarian Carcinoma. Int J Environ Res Public Health. 19(9): 5383. https://doi.org/10.3390/ijerph19095383 PMID: 35564776
  83. Awada Z, Bouaoun L, Nasr R, Tfayli A, Cuenin C, Akika R, et al. (2021). LINE-1 methylation mediates the inverse association between body mass index and breast cancer risk: A pilot study in the Lebanese population. Environ Res. 197: 111094. https://doi.org/10.1016/j.envres.2021.111094 PMID: 33839117
  84. Barupal DK, Schubauer-Berigan MK, Korenjak M, Zavadil J, Guyton KZ (2021). Prioritizing cancer hazard assessments for IARC Monographs using an integrated approach of database fusion and text mining. Environ Int. 156: 106624. https://doi.org/10.1016/j.envint.2021.106624 PMID: 33984576
  85. Camuzi D, Buexm LA, Lourenco SQC, Esposti DD, Cuenin C, Lopes MSA, et al. (2021). HPV Infection Leaves a DNA Methylation Signature in Oropharyngeal Cancer Affecting Both Coding Genes and Transposable Elements. Cancers (Basel). 13(14). https://doi.org/10.3390/cancers13143621 PMID: 34298834
  86. Cree IA, Indave Ruiz BI, Zavadil J, McKay J, Olivier M, Kozlakidis Z, et al. (2021). The International Collaboration for Cancer Classification and Research. Int J Cancer. 148(3): 560-571. https://doi.org/10.1002/ijc.33260 PMID: 32818326
  87. Faure MC, Khoueiry R, Quanico J, Acloque H, Guerquin MJ, Bertoldo MJ, et al. (2021). In Utero Exposure to Metformin Reduces the Fertility of Male Offspring in Adulthood. Front Endocrinol (Lausanne). 12: 750145. https://doi.org/10.3389/fendo.2021.750145 PMID: 34745014
  88. Fortuno C, Lee K, Olivier M, Pesaran T, Mai PL, de Andrade KC, et al. (2021). Specifications of the ACMG/AMP variant interpretation guidelines for germline TP53 variants. Hum Mutat. 42(3): 223-236. https://doi.org/10.1002/humu.24152 PMID: 33300245
  89. Ghantous A, Novoloaca A, Bouaoun L, Cuenin C, Cros MP, Xu Y, et al. (2021). Aflatoxin Exposure during Early Life Is Associated with Differential DNA Methylation in Two-Year-Old Gambian Children. Int J Mol Sci. 22(16). https://doi.org/10.3390/ijms22168967 PMID: 34445674
  90. Giuliani M, Gheit T, Rollo F, Tommasino M, Latini A, Benevolo M, et al. (2021). Predictors of Oral Infection by Mucosal and Cutaneous Human Papillomaviruses in HIV-Infected and Uninfected Men Who Have Sex with Men of the OHMAR Study. J Clin Med. 10(13): 9. https://doi.org/10.3390/jcm10132804 PMID: 34202235
  91. Jacobson S, Dahlqvist P, Johansson M, Svensson J, Billing O, Sund M, et al. (2021). Hyperglycemia as a risk factor in pancreatic cancer: A nested case-control study using prediagnostic blood glucose levels. Pancreatology. 21(6): 1112-1118. https://doi.org/10.1016/j.pan.2021.05.008 PMID: 34049822
  92. Karabegovic I, Portilla-Fernandez E, Li Y, Ma J, Maas SCE, Sun D, et al. (2021). Epigenome-wide association meta-analysis of DNA methylation with coffee and tea consumption. Nat Commun. 12(1): 2830. https://doi.org/10.1038/s41467-021-22752-6 PMID: 33990564
  93. Liew K, Yu GQS, Wei Pua LJ, Wong LZ, Tham SY, Hii LW, et al. (2021). Parallel genome-wide RNAi screens identify lymphocyte-specific protein tyrosine kinase (LCK) as a targetable vulnerability of cell proliferation and chemoresistance in nasopharyngeal carcinoma. Cancer Lett. 504: 81-90. https://doi.org/10.1016/j.canlet.2021.02.006 PMID: 33587980
  94. Lipenga T, Matumba L, Vidal A, Herceg Z, McCormack V, De Saeger S, et al. (2021). A concise review towards defining the exposome of oesophageal cancer in sub-Saharan Africa. Environ Int. 157: 106880. https://doi.org/10.1016/j.envint.2021.106880 PMID: 34543937
  95. Looi CK, Hii LW, Chung FF, Mai CW, Lim WM, Leong CO (2021). Roles of Inflammasomes in Epstein-Barr Virus-Associated Nasopharyngeal Cancer. Cancers (Basel). 13(8). https://doi.org/10.3390/cancers13081786 PMID: 33918087
  96. Nwanaji-Enwerem JC, Chung FF, Van der Laan L, Novoloaca A, Cuenin C, Johansson H, et al. (2021). An epigenetic aging analysis of randomized metformin and weight loss interventions in overweight postmenopausal breast cancer survivors. Clin Epigenetics. 13(1): 224. https://doi.org/10.1186/s13148-021-01218-y PMID: 34920739
  97. Rao A, Arvinden VR, Ramasamy D, Patel K, Meenakumari B, Ramanathan P, et al. (2021). Identification of novel dysregulated circular RNAs in early-stage breast cancer. J Cell Mol Med. 25(8): 3912-3921. https://doi.org/10.1111/jcmm.16324 PMID: 33544410
  98. Sharp GC, Alfano R, Ghantous A, Urquiza J, Rifas-Shiman SL, Page CM, et al. (2021). Paternal body mass index and offspring DNA methylation: findings from the PACE consortium. Int J Epidemiol. 50(4): 1297-1315. https://doi.org/10.1093/ije/dyaa267 PMID: 33517419
  99. Sklias A, Halaburkova A, Vanzan L, Jimenez NF, Cuenin C, Bouaoun L, et al. (2021). Epigenetic remodelling of enhancers in response to estrogen deprivation and re-stimulation. Nucleic Acids Res. 49(17): 9738-9754. https://doi.org/10.1093/nar/gkab697 PMID: 34403459
  100. Soares-Lima SC, Gonzaga IM, Camuzi D, Nicolau-Neto P, Vieira da Silva R, Guaraldi S, et al. (2021). IL6 and BCL3 Expression Are Potential Biomarkers in Esophageal Squamous Cell Carcinoma. Front Oncol. 11: 722417. https://doi.org/10.3389/fonc.2021.722417 PMID: 34422669
  101. Soares-Lima SC, Mehanna H, Camuzi D, de Souza-Santos PT, Simao TA, Nicolau-Neto P, et al. (2021). Upper Aerodigestive Tract Squamous Cell Carcinomas Show Distinct Overall DNA Methylation Profiles and Different Molecular Mechanisms behind WNT Signaling Disruption. Cancers (Basel). 13(12): 19. https://doi.org/10.3390/cancers13123014 PMID: 34208581
  102. Sorroche BP, Talukdar FR, Lima SCS, Melendez ME, de Carvalho AC, de Almeida GC, et al. (2021). DNA Methylation Markers from Negative Surgical Margins Can Predict Recurrence of Oral Squamous Cell Carcinoma. Cancers (Basel). 13(12): 17. https://doi.org/10.3390/cancers13122915 PMID: 34207933
  103. Talukdar FR, Soares Lima SC, Khoueiry R, Laskar RS, Cuenin C, Sorroche BP, et al. (2021). Genome-Wide DNA Methylation Profiling of Esophageal Squamous Cell Carcinoma from Global High-Incidence Regions Identifies Crucial Genes and Potential Cancer Markers. Cancer Res. 81(10): 2612-2624. https://doi.org/10.1158/0008-5472.CAN-20-3445 PMID: 33741694
  104. Woo HD, Herceg Z (2021). A Method to Investigate the Helicobacter pylori-Associated DNA Methylome. Methods Mol Biol. 2283: 75-81. https://doi.org/10.1007/978-1-0716-1302-3_9 PMID: 33765311

 

 
View Key Publications

 

 

Epigenomics and Mechanisms
About Research Publications Personnel
Close Reading Mode
UP